Is My Intel® NUC Compatible With an NVMe Drive?

SATA is just a complete wasted slot ; all slots should be dual NVMESATA capable, or

NVMe was designed for SSDs and communicates between the storage interface and the system's CPU using high-speed PCIe sockets without the limitations of form

candy blitz slot Yes, it is possible Though, I'll also say that I don't think any of my motherboards have an option to force the slots to SATA mode

can i put ddr3 in ddr4 slot No You can get an SATA drive